Enhancing Social Skills in Schizophrenia Spectrum Disorders - Oxytocin as add-on to Psychosocial Treatment

This study tests whether adding oxytocin — a naturally occurring hormone sometimes called the "social bonding" hormone — as a nasal spray improves social skills training for people with schizophrenia or related psychotic disorders. Many people with schizophrenia have difficulty with social interactions, and this trial investigates whether oxytocin can enhance the benefits of standard psychosocial treatment. **You may be eligible if:** - You are between 18 and 64 years old - You have a confirmed diagnosis of schizophrenia or another primary psychotic disorder - You have at least one moderate or severe negative symptom (such as reduced motivation, flat emotions, or social withdrawal) - You are receiving regular psychosocial (social or psychological) treatment at least twice a week **You may NOT be eligible if:** - You are outside the 18–64 age range - You do not have a diagnosis of schizophrenia or a related psychotic disorder - You have conditions that make oxytocin unsafe (e.g., certain hormonal conditions) - You are pregnant or breastfeeding - You are not currently in regular psychosocial treatment Talk to your doctor to see if this trial is right for you.