RecruitingNot ApplicableNCT06883851

Effectiveness of Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in Children With Primary Monosymptomatic Nocturnal Enuresis

Evaluating the Efficacy of Structured Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in the Management of Primary Monosymptomatic Nocturnal Enuresis in Children


Sponsor

Bahçeşehir University

Enrollment

40 participants

Start Date

Mar 11, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this randomized controlled trial is to evaluate the effects of Structured Pelvic Floor Muscle Rehabilitation (SPFMR) in children with Primary Monosymptomatic Nocturnal Enuresis (PMNE) who are undergoing desmopressin asetat (DDAVP) treatment prescribed by a pediatric urologist. The study aims to investigate whether SPFMR can reduce the frequency and severity of enuresis episodes and whether it can also reduce relapse rates in the short- and long-term follow-up. The main questions the study seeks to answer are: * Does SPFMR reduce the frequency and severity of enuresis episodes in children with PMNE? * Does SPFMR treatment reduce relapse rates in children with PMNE in the long term? Researchers will compare the group receiving SPFMR in addition to DDAVP treatment with a control group receiving only DDAVP treatment. This comparison will help evaluate the effect of SPFMR on the severity of enuresis episodes and relapse rates. Participants will: * Receive DDAVP treatment (SPFMR group and Control group) * Participate in SPFMR sessions ( SPFMR group) * Keep a diary of enuresis frequency and severity * Assess relapse during short- and long-term follow-up The hypotheses of the study are: H0: Adding SPFMR to desmopressin treatment for children with PMNE has no short-term effect on the severity of enuresis episodes. H1: Adding SPFMR to desmopressin treatment for children with PMNE has a short-term effect on the severity of enuresis episodes. H0: Adding SPFMR to desmopressin treatment for children with PMNE has no long-term effect on the severity of enuresis episodes. H2: Adding SPFMR to desmopressin treatment for children with PMNE has a long-term effect on the severity of enuresis episodes.


Eligibility

Min Age: 7 YearsMax Age: 13 Years

Inclusion Criteria6

  • Being between 7 and 13 years old
  • Diagnosed with primary MNE by a pediatric urology department within the last 6 months
  • No urinary tract infection verified by laboratory tests
  • Ability to communicate in Turkish and absence of mental deficit
  • No diagnosed psychiatric problems
  • Willingness to participate in the study (child and family)

Exclusion Criteria9

  • Presence of orthopedic conditions preventing evaluation
  • Anatomical anomalies in the urinary system
  • History of urinary system surgery
  • Neurological disorders
  • Presence of mental retardation
  • History of orthopedic surgery that could alter pelvic or lower extremity integrity
  • Receiving PFM rehabilitation in the last 6 months
  • Using nighttime alarm therapy in the last 6 months
  • Receiving any treatment for enuresis in the last 6 months

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Interventions

OTHERStructured pelvic floor rehabilitation

The classic DDVAP therapy will be administered by the pediatric urologist. The classic urotherapy training recommended for enuresis will be provided by the physiotherapist. In addition, structured pelvic floor muscle rehabilitation (SPFMR) will be provided by the physiotherapist for 10 weeks. Each session is planned to last approximately 60 minutes. SPFMR will include multiple interventions combined. Below is information about the brief interventions. * Diaphragmatic Breathing Training * Pelvic Floor Training with Biofeedback * Core Stabilization Exercises * Squat Exercises * External Rotator Strengthing * Adductor Strengthing * Balance Training * Home Exercises


Locations(2)

Private Selcuk Silay Pediatric Urology Clinic

Istanbul, Beşiktaş, Turkey (Türkiye)

Medipol Acıbadem Region Hospital

Istanbul, Kadıkoy, Turkey (Türkiye)

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NCT06883851