RecruitingNCT06884189

Application of Plant Protection Products (PPP) in Apple Orchards

Pilot Study on the Exposure of Operators, Residents and Workers to Plant Protection Products Used in Apple Orchards and Possible Health Effects

Sponsor

German Federal Institute for Risk Assessment

Enrollment

16 participants

Start Date

Mar 11, 2025

Study Type

OBSERVATIONAL

Conditions

Dermal Exposure Inhalative Exposure Metabolites in Urine Effekt Biomarker in Blood

Summary

The aim of the aPPPle pilot study is to test feasibility and generate first results in preparation for a main study. The aPPPle study will investigate the exposure of operators, workers and residents to plant protection products (PPP) and potential physiological effects on blood biomarkers. The target plants are apple crops, as application occurs at higher altitudes and therefore higher drift/exposure is expected compared to ground-level application. The substances to be investigated are acetamiprid (an insecticide) and dithianon and dodine (two fungicides).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This pilot study investigates how much exposure orchard workers, nearby residents, and others have to certain pesticides — specifically the insecticide acetamiprid and the fungicides dithianon and dodine — used in apple orchards, and whether that exposure affects blood biomarkers. Because pesticides are applied at elevated angles in orchards, drift and exposure are potentially higher than in other agricultural settings. Adults aged 18 and older who belong to one of the defined study groups (operators, workers, or community members living near the orchards) and have health insurance are eligible to participate. Participation involves providing blood samples and answering study questionnaires at defined time points during and after pesticide application season. This summary was generated with AI assistance and is intended to help patients understand the study in plain language.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Federal Institute for Risk Assessment

Berlin, Germany

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NCT06884189