RecruitingNot ApplicableNCT06885541

Detection of Internal Tremors by Oscillometry in Parkinson's Patient

Detection of Internal Tremors by Oscillometry in Parkinson's Patient : a Pilot Study

Sponsor

University Hospital, Toulouse

Enrollment

60 participants

Start Date

Feb 10, 2026

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease

Summary

The goal of the present study is to objectively access the presence of an Internal Tremor in Parkinson's disease. Inertial sensors will be used to detect the presence of a rhythmic oscillation of 3-4 Hz. The study will be performed in both Parkinson's disease patients and healthy controls to ascertain the specificity of this type of tremor.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria9

(For the experimental group)
Patient with idiopathic parkinson's disease
Mini Mental State Evaluation score above or equal to 25
Hoehn and Yahr scale score of ≤3 in the OFF phase, with postural stability allowing the patient to stand unaided for 1 minute.
Able to walk unassisted
Willing to undergo accelerometry in the OFF state
(For the control group)
Healthy volunteer subjects matched for age (+/- 5 years) and sex
Mini Mental State Evaluation score above or equal to 25

Exclusion Criteria12

(For the experimental group)
Patients with an atypical parkinsonian syndrome
Patients unable to walk or stand for more than one minute in the off state
Parkinson's patients treated with deep brain stimulation, apomorphine pump, or duodopa intestinal infusion, and foslevodopa
Pregnant patients
Major osteoarticular problems
Neurological condition that may affect gait
(For the control group)
Participants with significant gait impairment (osteoarticular disorder)
Those with a neurological disease that, in the investigator's judgment, may interfere with the study's outcome measure
Participants with a clinical tremor that may interfere with the measurement of the primary outcome (e.g., essential tremor, thyroid disease, or tremors induced by medication)
Pregnant participants