Single vs Hypofractionated Irradiation For Timely Access to Partial Breast Radiotherapy
Phase II Single vs Hypofractionated Irradiation For Timely Access to Partial Breast Radiotherapy: SHIFT-PB
British Columbia Cancer Agency
60 participants
Jun 8, 2026
INTERVENTIONAL
Conditions
Summary
Partial Breast Irradiation (PBI) is a targeted radiation approach commonly administered post-lumpectomy, specifically targeting the tumour bed. This targeted therapy reduces the exposure to other nearby tissues such as lungs, heart, and chest wall. However, traditional PBI treatment involves lengthy multiple fraction courses which presents a burden to patients from rural and remote communities, who must travel long distances to receive high quality cancer care. The purpose of this study is to compare single fraction (SF) PBI vs. multiple fraction (MF) PBI.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Participants randomized to Arm 1 will receive PBI with a dose of 26 Gy in 5 daily fractions.
Participants randomized to Arm 2 will receive PBI in a single fraction with a dose of 13 Gy.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06885671