RecruitingPhase 4NCT06886373

Optimizing the Ocular Surface With Systane COMPLETE Pre- and Post-operatively in Patients With Dry Eye Planning for Cataract Surgery: An Extension Study of Optimizing the Ocular Surface With Systane COMPLETE in Patients With Dry Eye Planning for Cataract Surgery


Sponsor

National Taiwan University Hospital

Enrollment

140 participants

Start Date

Mar 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Compare the corneal astigmatism data before and after the use of Systane COMPLETE to evaluate its impact on predicting changes in postoperative residual astigmatism, as well as the effects of using or not using Systane COMPLETE on preoperative and postoperative Ocular Surface Disease Index (OSDI) scores and Non-Invasive Tear Break-Up Time (NITBUT).


Eligibility

Min Age: 20 YearsMax Age: 85 Years

Inclusion Criteria2

  • Cataract patients aged between 20 and 85 years.
  • Patients with normal cognitive function who are able to complete the dry eye questionnaire (with - responses recorded by the research team) and are willing to undergo phacoemulsification and intraocular lens implantation under topical anesthesia.

Exclusion Criteria5

  • Unable to answer the questions in the dry eye survey.
  • Ocular trauma or ocular surgery in the planned surgical eye, active ocular infection, and obvious abnormalities in ocular surface or eyelid margins other than MGD cause decreased visual acuity other than cataracts.
  • Dry eye signs: Corneal Fluorescein Staining CFS (+) to exclude any corneal abnormalities or epithelial defect.
  • Systemic drug use, including tetracycline derivatives, antihistamines, and isotretinoin.
  • Using dry eye medication at screening stage.

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Interventions

DRUGSystane Complete

Systane COMPLETE is an artificial tears that contain nano-emulsion of mineral oil and phospholipids.


Locations(1)

National Taiwan University Hospital

Taipei, Taiwan

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NCT06886373


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