RecruitingNot ApplicableNCT06887829

Radio- KO Radiotherapy for Knee Osteoarthritis Clinical Trial

The Randomized Clinical Trial of Low-Dose Radiotherapy for Knee Osteoarthritis


Sponsor

Mayo Clinic

Enrollment

128 participants

Start Date

Jun 4, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The primary aim of this study is to investigate whether low-dose radiotherapy is an effective treatment to reduce the pain of knee osteoarthritis. A secondary aim is to determine whether patients experience any more measurable side effects than those receiving sham treatments.


Eligibility

Min Age: 50 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Low dose radiotherapy and Sham comparator for people with osteoarthritis, knee. The study is currently recruiting participants at 1 location. People eligible for this study include aged 50 Years to 85 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONLow dose radiotherapy

Participants will receive low dose radiotherapy (0.5 Gy) 3 times per week, for two weeks delivered via the X-Strahl Orthovoltage device.

OTHERSham comparator

Participants will receive identical treatment 3 times per week, for two weeks delivered via the X-Strahl Orthovoltage device, without radiation.


Locations(1)

Mayo Clinic

Rochester, Minnesota, United States

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NCT06887829


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