RecruitingNCT06889844

Observational Cross-reactivity Study for Colorectal Cancer Diagnosis

Observational Cross-reactivity Study to Evaluate the Specificity of a Blood Test for Colorectal Cancer Diagnosis Based on Molecular Markers and Risk Factors Identified With Artificial Intelligence Tools


Sponsor

ADVANCED MARKER DISCOVERY S.L.

Enrollment

250 participants

Start Date

Apr 17, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The objective of this observational study is to evaluate the false positive rate of the blood test based on molecular biomarkers and risk factors. A total of 250 patients diagnosed with various cancers and gastrointestinal diseases will be enrolled. The main question to be answered is Does the blood test have a low false positive rate in the main study population? Participants will donate a blood sample as part of their regular medical care for cancer diagnosis and give the consent to know their clinical risk factors.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study evaluates whether a diagnostic blood test for colorectal cancer also reacts to other cancers or gastrointestinal diseases — called "cross-reactivity." By testing blood from people with other GI conditions (but not colorectal cancer), researchers can understand whether the test might produce false positive results. **You may be eligible if...** - You are older than 18 - You have been diagnosed with only one type of cancer that is NOT colorectal cancer, or you have a gastrointestinal disease (but not colorectal cancer) - You can understand the study information and sign a consent form **You may NOT be eligible if...** - You have received chemotherapy or radiation therapy previously - You have two or more different cancer diagnoses - You have a condition that might interfere with blood test results Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTblood sampling

Patients will donate a blood sample for molecular analysis of molecular biomarkers in plasma, which being the only procedure in the study.


Locations(5)

Hospitales HM de Malaga

Málaga, Andalusia, Spain

Hospital Centro Médico Asturias

Oviedo, Cantabria, Spain

Hospital Universitario de Ourense

Ourense, Galicia, Spain

Hospital Universitario HM Sanchinarro

Madrid, Madrid, Spain

MD Anderson Cancer Centre

Madrid, Madrid, Spain

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NCT06889844


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