RecruitingNot ApplicableNCT06895837

Effect of Exercise on Appetite in Response to Meals During Energy Restriction

Acute Effect of Exercise on Appetite, Appetite-Regulatory Hormones, and Energy Intake During Energy Restriction in Healthy Men


Sponsor

University of Glasgow

Enrollment

14 participants

Start Date

Jul 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study's primary aim is to investigate the acute effect of an exercise bout (30 minutes) on appetite and appetite-regulatory hormone responses during energy restriction. The researchers will also test if the exercise bout influences ad libitum energy intake after a period of energy restriction. The researchers will compare three groups (control, severe-energy restriction, and severe-energy restriction with exercise) to see if exercise bout, during energy restriction, affects appetite, appetite-regulatory hormones, and energy intake in healthy men.


Eligibility

Sex: MALEMin Age: 18 YearsMax Age: 65 Years

Inclusion Criteria2

  • Males aged 18 years or older.
  • Have stable body mass for at least six months (within ±2 kg).

Exclusion Criteria9

  • Females
  • People who are younger than 18 or older than 65 years old.
  • Following a special diet (e.g. weight loss, vegetarian or vegan, etc.).
  • Have food allergies related to the study.
  • Have significant contraindications to exercise (e.g., an injury that would inhibit running).
  • Smoking.
  • Taking any medications.
  • Suffering from metabolic health issues, e.g., history of diabetes, cardiovascular disease, or eating disorders.
  • Have any mental health conditions.

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Interventions

OTHERSevere-energy restriction

The participants will receive only 25% of their estimated energy needs.

OTHERSevere-energy restriction with exercise

The participants will run on the treadmill for 30 minutes and receive 25% of their estimated energy needs.


Locations(1)

New Lister Building, Glasgow Royal Infirmary

Glasgow, United Kingdom

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NCT06895837


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