RecruitingNot ApplicableNCT06896903

Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing

Sponsor

Baylor Research Institute

Enrollment

50 participants

Start Date

May 21, 2025

Study Type

INTERVENTIONAL

Conditions

ANOCA - Angina With Non-obstructive Coronary Arteries INOCA (Ischemia With Non Obstructive Coronary Artery Disease)

Summary

This single-arm, multi-center, prospective study will assess the coronary flow reserve (CFR), index of microcirculatory resistance (IMR), and determinants thereof (transit time, Pa, Pd) in patients before and after intracoronary nitroglycerine.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Coronary reactivity testing with and without nitrates for people with anoca - angina with non-obstructive coronary arteries and inoca (ischemia with non obstructive coronary artery disease). The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTCoronary reactivity testing with and without nitrates

CRT will be performed in the left and right coronary arteries. Measurements will be obtained in each of the coronaries first without intracoronary nitrates followed by a dose of 200-500 mcg of intracoronary nitrates and repeat measurements.

Locations(1)

Baylor Scott & White The Heart Hospital - Plano

Plano, Texas, United States

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NCT06896903

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