Impact of Stem Cell Donation on Unrelated and Related Donors' Health.
Retrospective-prospective Observational Monocentric Study Evaluating the Impact of Stem Cell Donation on Unrelated and Related Donors' Health.
Fondazione IRCCS Policlinico San Matteo di Pavia
400 participants
Feb 3, 2023
OBSERVATIONAL
Conditions
Summary
Haematopoietic stem cell donation represents a unique chance for curing patients affected with onchohaematologic and inherited diseases.If a related donor is unavailable a unrelated donor must be used. For both categories an accurate physical and laboratory examination is mandatory to establish the eligibility to bone marrow or peripheral blood stem cell collection since side effects related to donation may occur. To ensure high standards of safety and satisfaction of unrelated stem cells donors dedicated guidelines are available. On the other hand, there is no unambiguous guidance on the management of the related donor and published data on donation and long term follow-up are scarce.
Eligibility
Inclusion Criteria2
- Family donors ≥18 years referred by the Hematology and Oncohematology Transplant Center Pediatric of the Foundation of Centro Donatori -SIMT, following the national and international guidelines after medical evaluation
- Volunteer donors from IBMDR registry ≥18 years, following the national and international guidelines after medical evaluation
Exclusion Criteria1
- Donors 18 \< years
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06905704