RecruitingNCT06905704

Impact of Stem Cell Donation on Unrelated and Related Donors' Health.

Retrospective-prospective Observational Monocentric Study Evaluating the Impact of Stem Cell Donation on Unrelated and Related Donors' Health.


Sponsor

Fondazione IRCCS Policlinico San Matteo di Pavia

Enrollment

400 participants

Start Date

Feb 3, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Haematopoietic stem cell donation represents a unique chance for curing patients affected with onchohaematologic and inherited diseases.If a related donor is unavailable a unrelated donor must be used. For both categories an accurate physical and laboratory examination is mandatory to establish the eligibility to bone marrow or peripheral blood stem cell collection since side effects related to donation may occur. To ensure high standards of safety and satisfaction of unrelated stem cells donors dedicated guidelines are available. On the other hand, there is no unambiguous guidance on the management of the related donor and published data on donation and long term follow-up are scarce.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria2

  • Family donors ≥18 years referred by the Hematology and Oncohematology Transplant Center Pediatric of the Foundation of Centro Donatori -SIMT, following the national and international guidelines after medical evaluation
  • Volunteer donors from IBMDR registry ≥18 years, following the national and international guidelines after medical evaluation

Exclusion Criteria1

  • Donors 18 \< years

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Locations(1)

Fondazione IRCCS Policlinico San Matteo di Pavia

Pavia, Pavia, Italy

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NCT06905704