Comparative Performance of 64Copper [64Cu]-SAR-bis-PSMA vs 68Ga PSMA-11 PET CT for the Detection of Prostate Cancer Recurrence in the Setting of Biochemical Failure Following Radical Prostatectomy

This study is comparing two types of PET scans that use different radioactive tracers — one using copper-64 and one using gallium-68 — to detect prostate cancer recurrence after the prostate has been surgically removed, to determine which scan is better at finding the cancer. **You may be eligible if...** - You are a male 18 or older - You previously had your prostate removed for prostate cancer confirmed by biopsy - Your PSA (a prostate cancer marker in the blood) is rising, specifically between 0.20 and 0.75 ng/mL - You have not yet had salvage radiation therapy - You have already had a gallium-68 PSMA PET/CT scan within the last 4 weeks **You may NOT be eligible if...** - You have already received or are not a candidate for salvage radiation therapy - You have another active cancer - You have had hormone or other systemic therapy for your prostate cancer Talk to your doctor to see if this trial is right for you.