RecruitingNCT06908538

Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain

Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain (VANISH)

Sponsor

AtriCure, Inc.

Enrollment

2,000 participants

Start Date

Apr 1, 2025

Study Type

OBSERVATIONAL

Conditions

amputation of lower limb Amputation Amputation, Traumatic/Surgery Amputation of Upper Limb Cryo Analgesia Amputation, Limb Loss

Summary

The goal of this Registry is to see how the device is used when freezing nerves during an amputation procedure.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called cryoablation for people with amputation, amputation of upper limb, and other related conditions. The study is currently recruiting participants at 4 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEcryoablation

Cryoanalgesia, also known as Cryoablation, Cryoneurolysis, or Cryonerve Block, has been used for decades to treat chronic pain and has recently been employed for the management of Phantom Limb Pain. Cryoanalgesia involves the use of a probe to apply extreme cold (approximately -70◦C) to induce reversible axonal injury and Wallerian degeneration to produce a temporary conduction block that is sustained until regeneration of the axon and sensation is restored, typically weeks to months later.