RecruitingPhase 1Phase 2NCT06909877

Study to Evaluate Efficacy and Safety of HH2853 in Relapsed/Refractory Peripheral T-cell Lymphoma

An Open-label, Multinational, Multicenter, Single-arm Phase Ⅰb/Ⅱ Study to Evaluate Efficacy and Safety of Oral HH2853, a Selective EZH1/2 Inhibitor, in Patients With Relapsed/Refractory Peripheral T-cell Lymphoma


Sponsor

Haihe Biopharma Co., Ltd.

Enrollment

100 participants

Start Date

Jul 27, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This study is a an open-label, multinational, multicenter, single-arm Phase Ⅰb/Ⅱ Study to Evaluate Efficacy and Safety of Oral HH2853 in Patients with Relapsed/Refractory Peripheral T-cell Lymphoma.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new drug called HH2853 in people with peripheral T-cell lymphoma (a type of blood cancer) that has relapsed (come back) or stopped responding to previous treatments, to see how safe it is and how well it works. **You may be eligible if...** - You have a confirmed diagnosis of T-cell lymphoma (including types like PTCL-NOS, AITL, ALCL, NKTCL, or other related subtypes) - Your cancer has been treated with at least one prior regimen but has returned or stopped responding - You have received no more than 5 prior lines of treatment - You are in good overall health **You may NOT be eligible if...** - You have not received prior treatment - Your cancer is a type not covered by the study - Your overall health or organ function is too poor Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGHH2853 Tablets

25mg, 100mg and 200 mg BID oral administration


Locations(1)

Sichuan Cancer Hospital

Chengdu, Chengdu, China

View Full Details on ClinicalTrials.gov

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NCT06909877


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