RecruitingNot ApplicableNCT06910449

Hemithoracic Arc Radiotherapy Post Pleural Decortication

Hemithoracic Volumetric Modulated Arc Radiotherapy as Part of Lung-Sparing Multimodality Therapy in Patients With Malignant Pleural Mesothelioma Phase II Trial


Sponsor

Cairo University

Enrollment

45 participants

Start Date

Nov 11, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Malignant Pleural Mesothelioma is an aggressive and refractory disease , the most aggressive treatment plan offered to these patients include trimodalitiy approach with chemotherapy as the mainstay of treatment . the rationale of post operative Radiotherapy is to sterilize the post operative volume to reduce local failure meanwhile minimizing toxicities in this trial we are going to assess the safety and efficacy of Radiotherapy in Mesothelioma patients poat Pleural decortication


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether radiation therapy given to the chest wall area after a surgical procedure to remove the lining around the lung (pleural decortication) helps control metastatic disease that has spread to the lung lining (pleura). **You may be eligible if...** - You have metastatic cancer that has spread to the pleura (lining around the lungs) - You have already undergone pleural decortication surgery - You are able to give informed consent **You may NOT be eligible if...** - Your lung function tests (breathing tests) are too poor to tolerate radiation - Your cancer has already recurred or is being treated with palliative intent only - You are unable to complete the full course of radiation or attend follow-up visits Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONhemithoracic Volumetric Arc Radiotherapy post Pleural decortication

post operative delivery of hemithoracic Volumetric Arc Radiotherapy


Locations(1)

national Cancer Institute Cairo university

Cairo, Fom Elkhalig, Egypt

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NCT06910449


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