RecruitingNot ApplicableNCT06910956

Deep Learning Using Chest X-Rays to Identify High Risk Patients for Lung Cancer Screening CT

Deep Learning Using Routine Chest X-Rays and Electronic Medical Record Data to Identify High Risk Patients for Lung Cancer Screening CT

Sponsor

Massachusetts General Hospital

Enrollment

1,500 participants

Start Date

May 20, 2025

Study Type

INTERVENTIONAL

Conditions

Lung Cancer Deep Learning Health Screening Early Cancer Detection

Summary

The goal of this clinical trial is to evaluate whether an AI tool that alerts providers to patients at high 6-year risk of lung cancer based on their chest x-ray images will improve lung cancer screening CT participation. The main question it aims to answer is: Does the AI tool improve lung cancer screening CT participation at 6 months after the baseline outpatient visit The intervention is an alert to the provider to discuss lung cancer screening CT eligibility, for patients considered at high risk of lung cancer based on CXR-LC AI tool. If there is a comparison group: Researchers will compare intervention and non-intervention arms to determine if lung cancer screen CT participation increases.

Eligibility

Min Age: 50 YearsMax Age: 77 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether a deep learning AI tool can analyze chest X-rays to identify people who are at high risk for lung cancer and should be referred for a low-dose CT lung screening scan. **You may be eligible if...** - You are between 50 and 77 years old - You currently smoke or are a former smoker, and may be eligible for lung cancer screening under Medicare guidelines - You have had a chest X-ray within the past 2 years - You have a scheduled outpatient appointment with a participating provider **You may NOT be eligible if...** - You have a history or signs or symptoms of lung cancer - You have had a chest CT scan within the past 2 years - You already have a clinical reason for a chest CT beyond screening purposes Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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