Deep Learning Using Chest X-Rays to Identify High Risk Patients for Lung Cancer Screening CT
Deep Learning Using Routine Chest X-Rays and Electronic Medical Record Data to Identify High Risk Patients for Lung Cancer Screening CT
Massachusetts General Hospital
1,500 participants
May 20, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to evaluate whether an AI tool that alerts providers to patients at high 6-year risk of lung cancer based on their chest x-ray images will improve lung cancer screening CT participation. The main question it aims to answer is: Does the AI tool improve lung cancer screening CT participation at 6 months after the baseline outpatient visit The intervention is an alert to the provider to discuss lung cancer screening CT eligibility, for patients considered at high risk of lung cancer based on CXR-LC AI tool. If there is a comparison group: Researchers will compare intervention and non-intervention arms to determine if lung cancer screen CT participation increases.
Eligibility
Inclusion Criteria3
- Scheduled outpatient appointment with participating provider.
- to 77-year-old who currently or formerly smoked, to include persons potentially eligible for lung screening based on Medicare guidelines.
- Recent (within 2 years) PA chest radiograph.
Exclusion Criteria1
- • History or signs/symptoms of lung cancer. Recent (within 2 years) chest CT. Clinical indication for chest CT beyond lung cancer screening.
Interventions
Alert to provider to discuss lung cancer screening CT eligibility, for patients considered at high risk of lung cancer based on CXR-LC AI tool.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06910956