RecruitingNot ApplicableNCT06910969

Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease

Multi-Site Randomized Controlled Trial of A Multidisciplinary Intervention for Adults With Chronic Graft Versus Host Disease


Sponsor

Massachusetts General Hospital

Enrollment

350 participants

Start Date

Aug 13, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to demonstrate the efficacy of a multidisciplinary group-based telehealth intervention (HORIZONS) compared to minimally enhanced usual care for improving self-management and quality of life for hematopoietic stem cell transplant (HSCT) survivors living with chronic graft-versus host disease, and to identify critical facilitators and barriers for HORIZONS implementation and adoption.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called HORIZONS Intervention and a behavioral approach called Minimally enhanced usual care for people with bone marrow transplant complications and graft-versus-host disease. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALHORIZONS Intervention

Therapist-delivered multidisciplinary group-based telehealth intervention comprised of 8 sessions

BEHAVIORALMinimally enhanced usual care

Receiving a standardized booklet with evidence-based information on chronic GHVD management and HST survivorship recommendations


Locations(2)

University of Miami Sylvester Comprehensive Cancer Center

Miami, Florida, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

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NCT06910969


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