RecruitingNCT06916195

Burden of Cytomegalovirus Reactivation in Pediatric Patients After Allogeneic Hematopoietic Stem Cell Transplantation

CMV PED Study - A Retrospective Observational Study To Understand The Clinical And Economic Burden Associated With Cytomegalovirus Reactivation and Related Health Outcomes In Pediatric Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation In Italy


Sponsor

MSD Italia S.r.l.

Enrollment

230 participants

Start Date

May 9, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This observational retrospective analysis will provide useful information for clinicians and payers, and local guidelines committee members, to improve the understanding of Cytomegalovirus clinical and economic burden and clinical management of pediatric patients undergoing allogeneic Hematopoietic Stem Cells Transplantation in Italy.


Eligibility

Min Age: 0 YearsMax Age: 18 Years

Inclusion Criteria3

  • Patients from birth to less than 18 years of age (at the moment of the allogeneic HSCT);
  • Patients who received allogeneic HSCT between January 2018 and June 2020;
  • Patients (or their legally acceptable representatives) must have signed and dated the Informed Consent \& Privacy Form (ICF), if applicable.

Exclusion Criteria1

  • Letermovir use at any time

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Locations(5)

IRCCS Istituto Giannina Gaslini, Trapianto di Cellule Staminali Emopoietiche, Dipartimento di Onco-Ematologia Pediatrica

Genova, Italy

Ospedale San Gerardo, Clinica Pediatrica

Monza, Italy

Azienda Ospedale-Università di Padova, Clinica di Oncoematologia Pediatrica

Padova, Italy

IRCCS Ospedale Pediatrico Bambino Gesù, Dipartimento di Pediatria Ematologia e Oncologia

Roma, Italy

Ospedale Infantile Regina Margherita, Dipartimento Patologia e Cura del Bambino

Torino, Italy

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NCT06916195


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