RecruitingNCT06916624

Multicenter Study of 18F-Labeled NY104 for PET/CT Imaging in Renal Cell Carcinoma


Sponsor

The Affiliated Hospital of Qingdao University

Enrollment

40 participants

Start Date

Apr 12, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Study on the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 18F-NY104 PET/CT in diagnosing primary, recurrent, and metastatic lesions of renal cell carcinoma; and investigate the effect of oral low-dose CAIX inhibitor (Acetazolamide) on the tissue distribution of 18F-NY104 in renal cell carcinoma patients, particularly in the stomach and kidneys.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new PET/CT imaging agent called 18F-NY104 to see how well it can detect and visualize renal cell carcinoma (kidney cancer), including recurrent or metastatic disease. It is an imaging study, not a treatment trial. **You may be eligible if...** - You are between 18 and 75 years old - You have been diagnosed with or are suspected to have kidney cancer (renal cell carcinoma), or there is suspicion of recurrence or spread after prior treatment - You have at least one measurable lesion on imaging - Your blood counts, liver, and kidney function are within acceptable ranges - You are willing to use effective contraception during and for 6 months after the study **You may NOT be eligible if...** - You have had major surgery or trauma within the past 4 weeks - You have a severe systemic infection or significant organ dysfunction - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATION18F-NY104 PET/CT

The radionuclide ¹⁸F will serve as the tracer in this study. NY104 will be labeled with \[¹⁸F\]AlF to form the ¹⁸F-NY104 injection for use in this research.All participants will undergo ¹⁸F-NY104 PET scan.


Locations(1)

The Affiliated Hospital of Qingdao University

Qingdao, Shandong, China

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NCT06916624


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