RecruitingNCT06917053

Renal Perfusion and the Development of AKI Following Traumatic Injury

Renal Perfusion and the Development of AKI Following Traumatic Injury - A Longitudinal Observational Cohort Study


Sponsor

King's College Hospital NHS Trust

Enrollment

20 participants

Start Date

Apr 13, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Acute kidney injury (AKI) is a complication of traumatic haemorrhagic shock (THS) and together these conditions increase mortality risk. Although septic shock patients who develop severe AKI are known to develop hypoperfusion of the renal cortex, little is known regarding intra-renal perfusion changes in THS. The aim of the current study is to investigate the effects of THS on renal microcirculatory perfusion.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Sublingual incident dark field videomicroscopy, a medical device called Ultrasound (including contrast enhanced ultrasound), and others for people with aki (acute kidney injury) due to trauma, aki - acute kidney injury, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEUltrasound (including contrast enhanced ultrasound)

Ultrasound measures: contrast enhanced ultrasound (CEUS) of the kidney, venous excess ultrasound (VExUS), echocardiography

DEVICESublingual incident dark field videomicroscopy

Sublingual incident dark field (IDF) videomicroscopy

DEVICEUrinary oxygen tension.

Continuous urinary oxygen tension


Locations(1)

King's College Hospital

London, United Kingdom

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NCT06917053


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