RecruitingPhase 4NCT06925152

COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block

Sponsor

University of Tennessee

Enrollment

120 participants

Start Date

Jul 15, 2025

Study Type

INTERVENTIONAL

Conditions

cesarean delivery Postoperative pain control perioperative pain management Complex Obstetric Surgery

Summary

To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean delivery (CD) in the setting of complex obstetric surgery (COS).

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Bupivicaine intervention arm and a drug called Placebo arm for people with complex obstetric surgery, postoperative pain control, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years to 50 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGBupivicaine intervention arm

TAP blocks in intervention group will include 0.5% bupivacaine in 30mL solution of 15mL normal saline and 15mL bupivacaine

DRUGPlacebo arm

Placebo group TAP block syringe will include 30mL normal saline

Locations(1)

Regional One Health

Memphis, Tennessee, United States

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NCT06925152

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