Using Xe MRI to Guide Radiation Therapy for Lung Cancer
Image-Based Functionally Adapted Radiation Therapy for Lung Cancer
Sean Fain
15 participants
Aug 30, 2025
INTERVENTIONAL
Conditions
Summary
The purpose of this research study is to explore using MRI scans with xenon to better image lung function, how lung function changes after radiation therapy, and to guide radiation therapy away from parts of the lung that have good function. This project is foundational to performing additional studies to establish if novel MRI imaging can serve as a guidance tool for lung cancer radiation treatment.
Eligibility
Plain Language Summary
Simplified for easier understanding
This is a simplified summary. Always discuss eligibility with your doctor before enrolling in a clinical trial.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
MRI with Xenon used for contrast
Pulmonary function testing will include spirometry, lung volumes, DLCO and oscillometry
European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30+QLQ-LC29)
modified Medical Research Council Dyspnea score (mMRC Dyspnea)
St. George's Respiratory Questionnaire (SGRQ)
blood biomarkers of inflammation and injury (e.g. Angiopoetin-2, Interleukin-6, myofibroblast activity, BPD4)
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06925295