Interpersonal Communication Training and Vaccination Workflow Training Alone and in Combination to Improve Communication and Recommendations About HPV Vaccination in Pharmacies, IMPACT HPV Trial
Implementing a Proactive Approach to Communicate and Teach About HPV Vaccination in Pharmacies: IMPACT HPV Study
Fred Hutchinson Cancer Center
1,900 participants
Oct 15, 2026
INTERVENTIONAL
Conditions
Summary
This clinical trial compares usual care to interpersonal communication training and vaccination workflow training, alone or in combination, for improving communication about and recommendations for human papillomavirus (HPV) and other vaccinations in pharmacies. Low HPV vaccination in the United States has placed unvaccinated children at risk of developing cancers as adults that could have been prevented. Pharmacies can be convenient for vaccination because they are open longer hours, have shorter wait times, can see patients without appointments and may cost less. However, many people are not aware that vaccination is available in pharmacies and some pharmacies lack the commitment from staff to vaccinate or may not have protocols in place for vaccination. Proactive communication approaches to recommending HPV vaccination have been shown to be effective in medical offices but have not been tested in the pharmacy setting. Interpersonal communication training incorporates the 5 A's (assess, advice, agree, assist and arrange) behavioral counseling framework to strongly recommend HPV and other vaccines and effectively answer any questions or concerns about vaccination. Vaccination workflow training establishes vaccination decision support strategies that pharmacies use to improve vaccination workflows. Interpersonal communication training and vaccination workflow training alone or in combination may improve communication and recommendations for HPV vaccination and increase HPV vaccination in pharmacies.
Eligibility
Plain Language Summary
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Interventions
Provide vaccinations per usual care
Review messages on safety and side effects
Review messages on vaccine effectiveness
Review messages on sexual activity
Review messages on HPV vaccine for boys
Review message on age to start vaccine
Review messages on school entry requirements
Ancillary studies
Complete a survey
Ancillary studies
Receive interpersonal communication training
Receive the vaccination workflow training
Provide vaccinations using the interpersonal communication strategy
Provide vaccinations using the vaccination workflow training strategy
Provide vaccinations using both the interpersonal communication strategy and the vaccination workflow training strategy
Locations(2)
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NCT06926062