Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery
Chinese University of Hong Kong
90 participants
Mar 25, 2025
INTERVENTIONAL
Conditions
Summary
Robotic assisted surgery has been performed for more than two decades with good success and safety profile. However, there was only one dominating robotic surgical system available in the past which led to high cost for robotic surgery. Recently, a new robotic surgical system (Sentire Robotic Surgical System) was introduced by researchers of The Chinese University of Hong Kong (CUHK). This new robotic surgical system aims to achieve similar outcomes and standards of robotic surgery performed using the dominating system but with a significantly lower cost. The technologic innovation and development of this new robotic system is made by the Cornerstone Robotics Limited, which is based in Hong Kong. In a pilot clinical study conducted at Prince of Wales Hospital involving 55 patients, the Sentire Robotic Surgical System had demonstrated high success rate with minimal complications in patients who underwent robotic colorectal, upper gastrointestinal, and urologic surgery. Researchers of CUHK would therefore like to conduct another prospective study to further evaluate the efficacy and safety of Sentire Surgical System C1000 in major gastrointestinal and urologic surgery with expanded indications. It is believed that the results of this study will provide data to support its use for wide range of procedures with minimal access trauma, for the benefit of patients. This system will also lead to a wider range of clinical application for minimally invasive surgery with a cost-effective model.
Eligibility
Inclusion Criteria14
- Body mass index \<35 kg/m2
- Suitable for the listed minimally invasive surgical procedures for treatment of respective diseases
- Willingness to participate as demonstrated by giving informed consent
- \- Adenocarcinoma or large adenoma (not amenable to endoscopic removal) located at the colorectum (from the cecum to the anal verge) amenable to minimally invasive surgery
- \- Mid/low rectal adenocarcinoma located \<12 cm from the anal verge
- Clinically diagnosed with previously untreated and uncomplicated rectal prolapse or enterocele
- \- Clinically diagnosed with nonmetastatic adenocarcinoma of prostate
- \- Clinically diagnosed with nonmetastatic kidney cancer
- \- Clinically diagnosed with nonmetastatic bladder cancer
- Robotic Esophageal Hiatal Surgery and Fundoplication
- \- Clinically diagnosed with Hiatal Hernia and / or Gastroesophageal reflux disease amendable to fundoplication
- \- Clinical diagnosis of gastric tumor (Adenocarcinoma or Gastrointestinal Stromal Tumor (GIST)) amendable to minimally invasive radical gastrectomy
- \- Clinical diagnosis of carcinoma of esophagus amendable to minimally invasive esophagectomy
- \- Symptomatic gallbladder stones clinically indicated for laparoscopic cholecystectomy
Exclusion Criteria33
- Contraindication to general anesthesia
- Severe concomitant illness that drastically shortens life expectancy or increases risk of therapeutic intervention
- Untreated active infection
- Noncorrectable coagulopathy
- Presence of another malignancy or distant metastasis
- Emergency surgery
- Vulnerable population (e.g., mentally disabled, pregnancy)
- Robotic Colorectal Resection
- T4 tumor
- Recurrent tumor
- Extensive previous abdominal surgery precluding minimally invasive surgery
- Robotic Transanal Total Mesorectal Excision
- T4 tumor or involvement of circumferential resection margin even after neoadjuvant therapy
- Tumor requiring multivisceral resection
- Tumor requiring abdominoperineal resection; recurrent rectal tumor
- T1 tumor that can be treated by local excision
- Extensive previous abdominal surgery
- Robotic Rectopexy
- \- Extensive previous abdominal surgery precluding minimally invasive surgery
- Radical Prostatectomy
- \- Previous history of prostate surgery (e.g., transurethral resection of prostate)
- Total or Partial Nephrectomy
- Previous ipsilateral kidney surgery
- Complex kidney anatomy (e.g., horseshoe kidney, complex renal vascular anatomy)
- Radical Cystectomy
- \- Previous history of laparotomy precluding minimally invasive surgery
- Robotic Gastrectomy
- \- Previous history of laparotomy precluding minimally invasive surgery
- Robotic Esophagectomy
- \- Esophageal carcinoma after definitive chemoradiotherapy and indicated for salvage esophagectomy
- Robotic Cholecystectomy
- Acute cholecystitis
- Previous history of abdominal surgery
Interventions
Robotic surgery using the Sentire Surgical System
Locations(1)
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NCT06926374