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RecruitingNot ApplicableNCT06928844

Role of Low Dose Injectable Progesterone in Triggering Ovulation

Role of Low Dose Injectable Progesterone in Triggering Ovulation: A Randomized Controlled Trial

Sponsor

The General Authority for Teaching Hospitals and Institutes

Enrollment

120 participants

Start Date

Apr 15, 2025

Study Type

INTERVENTIONAL

Conditions

Low DoseProgesteroneTriggering Ovulation

Summary

The aim of this study is to evaluate the role of low dose injectable progesterone in triggering ovulation.

Eligibility

Sex: FEMALEMin Age: 20 YearsMax Age: 35 Years

Inclusion Criteria3

  • Age from 20 to 35 years.
  • Infertile women.
  • Basal follicle-stimulating hormone (FSH) level <10 mIU/ml.

Exclusion Criteria6

  • Poor ovarian reserve.
  • Immunological disease.
  • Endometriosis.
  • Uterine abnormality.
  • Body mass index (BMI) >30 kg/m2.
  • Endometrial thickness <8 or >12 mm on the day of triggering.

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Interventions

DRUGProgesterone

Women will receive low dose progesterone 5 mg intramuscularly as a study group. (Letrozole 2.5 mg/day will be given from cycle day 3 onwards for only 5 days).

DRUGPlacebo

Women will receive placebo as a control group. (Placebo 2.5 mg/day will be given from cycle day 3 onwards for only 5 days).

Locations(1)

Teaching Hospitals and Institutes

Cairo, Egypt

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NCT06928844