RecruitingNCT06934863

Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center Experience

Observational Study of an OLP Patients Cohort: Characteristics, Comorbidities, Risk Factors for Malignant Transformation


Sponsor

Catholic University of the Sacred Heart

Enrollment

300 participants

Start Date

Jan 31, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The main objective of this paper will be to evaluate the rate of malignant transformation among a cohort of patients affected by oral lichen planus with long-term follow-up. Secondary aims will be to study and describe the characteristics of these patients to identify potential risk factors for malignant transformation, and to evaluate the therapeutic effects and features to OLP drgus.


Eligibility

Inclusion Criteria3

  • Clinical-histological diagnosis of Oral lichen planus
  • Patients who gave consensus to personal data treatment
  • Minimum 6 months follow-up

Exclusion Criteria4

  • Patients who did not give consensus to personal data treatment
  • Oral lichenoid lesions
  • Patients with anamnesis of hematopoietic stem cells transplant
  • Patients with a OSCC at the first histological examination (i.e., namely: also OSCC patients with a OLP background were excluded)

Locations(1)

Catholic University of the Sacred Heart

Roma, Italy, Italy

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NCT06934863


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