RecruitingNCT06934863

Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center Experience

Observational Study of an OLP Patients Cohort: Characteristics, Comorbidities, Risk Factors for Malignant Transformation


Sponsor

Catholic University of the Sacred Heart

Enrollment

300 participants

Start Date

Jan 31, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The main objective of this paper will be to evaluate the rate of malignant transformation among a cohort of patients affected by oral lichen planus with long-term follow-up. Secondary aims will be to study and describe the characteristics of these patients to identify potential risk factors for malignant transformation, and to evaluate the therapeutic effects and features to OLP drgus.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is examining how often a condition called oral leukoplakia — white patches inside the mouth — turns into oral cancer, and what characteristics predict that transformation. Understanding this can help doctors identify which patients need closer monitoring and earlier intervention. **You may be eligible if...** - You have been diagnosed with oral leukoplakia (white patches in your mouth) - You are receiving care at a participating dental or oral medicine clinic - You are an adult willing to have your condition tracked over time **You may NOT be eligible if...** - Your oral lesions have already been confirmed as cancer - You have conditions that make follow-up visits impossible - You have had prior treatment for oral cancer Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Catholic University of the Sacred Heart

Roma, Italy, Italy

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NCT06934863


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