RecruitingNCT06935864

Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors

The Prognostic Value of Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors


Sponsor

Ain Shams University

Enrollment

30 participants

Start Date

Aug 16, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The current study is to assess the prognostic value of Krüppel-like factors 4 and 7 in bone tumors, and its role in the disease progression.


Eligibility

Min Age: 1 MonthMax Age: 39 Years

Inclusion Criteria1

  • Age: children, young adolescents younger than 15 years, and young adults (15 to 39 years) Gender: Males and female. Histologically confirmed patients with skeletal or extra-skeletal OS or ES. Both localized and metastatic disease stages.

Exclusion Criteria1

  • Patients with second malignant bone sarcoma. Patients with benign bone tumors.

Interventions

DIAGNOSTIC_TESTKLF factor (4 and 7)

Immunohistochemical staining of 4 um sections prepared from paraffin blocks using KLF factor (4 and 7) by automated immunostaining using the streptavidin-biotin technique.


Locations(2)

Ain Shams University

Cairo, Egypt

Faculty of Medicine Ain Shams Research Institute- Clinical Research Center (MASRI-CRC)

Cairo, Egypt

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NCT06935864


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