Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors

This study is looking at the expression of proteins called KLF4 and KLF7 (Krüppel-Like Factors) in bone tumors. These proteins play a role in cell growth and behavior, and understanding their levels in bone tumors may help doctors predict how aggressive a tumor is and guide treatment choices. **You may be eligible if...** - You have been diagnosed with a bone tumor (benign or malignant) - You are undergoing surgery or biopsy where tissue samples will be collected - You consent to having your tumor tissue analyzed for research **You may NOT be eligible if...** - You decline to have your tissue samples used for research - Your tumor is not accessible for safe tissue sampling - You have conditions that prevent safe surgical or biopsy procedures Talk to your doctor to see if this trial is right for you.