the Effect of Hyaluronic Acid Intrauterine Wash on Endometrial Receptivity and Pregnancy Outcome
the Effect of Hyaluronic Acid Platelets Rich Plasma on the Endometrial Receptivity and Intracytoplasmic Sperms Injection Outcome
Al-Nahrain University
120 participants
Sep 1, 2023
INTERVENTIONAL
Summary
Hyaluronic acid intrauterine wash is done for infertile females undergoing intracytoplasmic sperm injection on the day of oocyte retrieval. endometrial receptivity parameters, including the subendometrial vasculature indices were measured before and after the intervention for purpose of studying the effect of hyaluronic acid on improvement of the endometrial receptivity and subsequently the pregnancy outcome
Eligibility
Inclusion Criteria3
- Infertile females aged 18-40 years.
- Infertile females scheduled for GnRH antagonist protocol of fresh ICSI cycle.
- Females use dual stimulation (GnRH agonist plus Ovetrelle) for ovulation triggering.
Exclusion Criteria5
- Infertile females diagnosed as a poor responder.
- Infertile females diagnosed with uterine pathology.
- Infertile females who are scheduled for a frozen ICSI cycle.
- Infertile females diagnosed with endocrine diseases like thyroid disease, diabetes mellitus, and hyperprolactinemia.
- Infertile females diagnosed with thrombocytopenia.
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Interventions
hyaluronic acid PRP preparation used to wash the endometrium on the day of oocytes retrieval
PRP preparation used to wash the uterine cavity on the day of oocytes retrieval
Locations(1)
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NCT06937645