RecruitingNot ApplicableNCT06942949

Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial


Sponsor

Avvio Medical

Enrollment

101 participants

Start Date

May 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the safety and performance of the ELS to treat urinary stones. The ELS is intended to break urinary stones into small fragments that can pass during or after the procedure with less or no discomfort. Eligible patients are male or females, age 21 or older, with a single urinary stone in the ureter. Participants will undergo the ELS procedure and then be evaluated 30 days later for the presence or absence of urinary stone fragments on a CT scan. Subjects who still have stone present at Day 30 will be evaluated again at Day 60. Other outcome measures will be changes in pain, quality of life, and return to normal daily activities/work.


Eligibility

Min Age: 21 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called ELS (Enhanced Lithotripsy System) for people with kidney calculi; ureteral calculi. The study is currently recruiting participants at 16 locations. People eligible for this study include aged 21 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEELS (Enhanced Lithotripsy System)

ELS (Enhanced Lithotripsy System) utilizes low pressure ultrasound to actuate proprietary microbubbles administered into the urine to pit and fragment urinary stones.


Locations(20)

Arizona State Urological Research Institute

Phoenix, Arizona, United States

Arkansas Urology Research Center

Little Rock, Arkansas, United States

Michael G. Oefelein Clinical Trials

Bakersfield, California, United States

San Diego Clinical Trials

La Mesa, California, United States

Golden State Urology

Sacramento, California, United States

University of Miami Hospital

Miami, Florida, United States

Georgia Urology

Roswell, Georgia, United States

Comprehensive Urologic Care

Lake Barrington, Illinois, United States

Wichita Urology Group

Wichita, Kansas, United States

Minnesota Urology

Woodbury, Minnesota, United States

Nebraska Urology

Lincoln, Nebraska, United States

Urology Nevada

Reno, Nevada, United States

University of Rochester Medical Center

Rochester, New York, United States

SUNY - Upstate Medical University

Syracuse, New York, United States

Duke

Durham, North Carolina, United States

Urology Specialists Clinic

Sioux City, South Dakota, United States

Urology San Antonio

San Antonio, Texas, United States

University of Virginia

Charlottesville, Virginia, United States

University of Virginia Community Health

Culpeper, Virginia, United States

Urology of Virginia

Virginia Beach, Virginia, United States

View Full Details on ClinicalTrials.gov

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NCT06942949