RecruitingNot ApplicableNCT06944392

Evaluating Pumpkin Seed Oil Extract Supplementation on Bladder Function

Sponsor

Northwestern University

Enrollment

40 participants

Start Date

Apr 11, 2025

Study Type

INTERVENTIONAL

Conditions

Overactive Bladder (OAB)

Summary

This is a pilot study to assess using validated outcome measures how ingesting pumpkin seed oil extract supports patient bladder function in a United States population.

Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria1

All patients evaluated at Northwestern's IPHP who report bladder function consistent with overactive bladder (urinary urgency, with or without urinary frequency more than 8 times daily or nocturia, with or without urgency urinary incontinence) at their index visit, who are also willing to use a dietary supplement and not initiate additional behavioral, medication or procedural treatment for 12 weeks following pumpkin seed oil extract initiation.

Exclusion Criteria11

Patients with any of the following will be excluded from the study:
Use of other supplements that contain pumpkin seed oil
≥Stage 3 pelvic organ prolapse
Urinary post-void residual ≥150cc
Culture-proven urinary tract infection at time of study enrollment
Recurrent urinary tract infection
Neurogenic bladder
Abdominal or pelvic malignancy
Initiation of new overactive bladder medications or supplements during study period or in the 3 months immediately preceding study enrollment
History of surgery in the past 12 months for pelvic organ prolapse, stress urinary incontinence, urgency urinary incontinence, or fecal or flatal incontinence
Patient's primary language is not English