The Safety and Effectiveness of Hyperthermic Intraperitoneal Chemotherapy Combined With Intravenous Chemotherapy for Peritoneal Metastatic Pancreatic Cancer, a Phase II Clinical Trial

This study is testing whether combining heated chemotherapy directly into the abdominal cavity (called HIPEC — hyperthermic intraperitoneal chemotherapy) with standard intravenous chemotherapy can be safe and effective for pancreatic cancer that has spread inside the abdomen (peritoneal metastasis). **You may be eligible if...** - You are between 18 and 80 years old - You have pancreatic cancer that has spread to the lining of the abdomen (peritoneal metastasis), confirmed by imaging or during surgery - You have not received any prior cancer treatments (surgery, chemotherapy, radiation, etc.) - You are in good enough health to undergo surgery (ECOG 0–1) **You may NOT be eligible if...** - You have already received anti-cancer treatment - Your overall health makes surgery too risky - Your cancer has spread to organs beyond the abdomen - You have significant other illnesses that would interfere with the treatment Talk to your doctor to see if this trial is right for you.