RecruitingPhase 4NCT06946914

Misoprostol Before Caesarean Section

Misoprostol Administration Before Elective Caesarean Section to Reduce the Risk of Respiratory Morbidity in Newborns


Sponsor

Kafrelsheikh University

Enrollment

160 participants

Start Date

Jun 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of our study is to evaluate the efficacy of Misoprostol before elective cesarean section in pregnant women with gestational age less than 38 weeks for preventing the occurrence of neonatal respiratory morbidity.


Eligibility

Sex: FEMALEMin Age: 20 YearsMax Age: 35 Years

Inclusion Criteria5

  • Women with indication for elective caesarean section.
  • Age less than 35 years old.
  • Gestational age less than 38 weeks.
  • Gestational age will be confirmed by certain LMP or reliable early ultrasound measurement of crown-rump length.
  • Singleton pregnancy with no major anomalies

Exclusion Criteria4

  • Any obstetric disorders as preeclampsia and diabetes.
  • Fetus with oligohydramnios, intrauterine growth restriction.
  • Any contraindications to misoprostol like those with previous allergic reaction or hypersensitivity to prostaglandin hemorrhagic disorders, and severe anemia.
  • History of more than or equal 2 previous caesarean section.

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Interventions

DRUGMisoprostol

administration of 100mg of misoprostol to evaluate the efficacy of Misoprostol before elective cesarean section in pregnant women with gestational age less than 38 weeks for preventing the occurrence of neonatal respiratory morbidity.


Locations(1)

Kafr El-sheikh University Hospital

Kafr Ash Shaykh, Egypt, Egypt

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NCT06946914


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