Safety and Efficacy of Glumetinib Combined With Docetaxel for Injection (Albumin-bound) in Patients With Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma and Other Solid Tumors
A Multicenter, Open-label, Phase II Clinical Study to Evaluate the Safety and Efficacy of Glumetinib Combined With Docetaxel for Injection (Albumin-bound) in Patients With Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma and Other Solid Tumors With MET Overexpression and/or Amplification
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
350 participants
Jun 4, 2025
INTERVENTIONAL
Conditions
Summary
The trial consists of Stage 1 (including dose escalation and dose expansion) and Stage 2 (proof-of-concept study). Among them, Stage 2 adopts a randomized, controlled, open-label, and multicenter design.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
glumetinib once daily once daily under fasting conditions in each 21-day treatment cycle.
Docetaxel for Injection (Albumin-bound) by intravenous injection in each 21-day treatment cycle.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06947291