RecruitingNot ApplicableNCT06948760

Testing a Conversion Factor for a More Rapidly Acting Insulin in an Automated Insulin Delivery System Among Adolescents With T1D

Testing a Conversion Factor for a More Rapidly Acting Insulin in an Automated Insulin Delivery System Among Adolescents With T1D [Launchpad Lyumjev]


Sponsor

Mark D. DeBoer, MD, MSc., MCR

Enrollment

20 participants

Start Date

Jul 23, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

A randomized controlled trial of Control-IQ, assessing glycemic control (time-in-range 70-180 mg/dL) for Lyumjev insulin (in which the insulin settings have been determined using an experimental conversion factor) as compared to Humalog or Novolog (using optimized settings)


Eligibility

Min Age: 12 YearsMax Age: 22 Years

Plain Language Summary

Simplified for easier understanding

This study is exploring a more precise way to dose fast-acting insulin for teenagers and young adults who use an automated insulin pump system called the Tandem t:slim with Control-IQ Technology. The goal is to find the best conversion factor when switching to a faster insulin, so that blood sugar levels stay in range more effectively. **You may be eligible if...** - You are between 12 and 22 years old - You have had type 1 diabetes for at least one year - Your HbA1c (a measure of average blood sugar) is between 6.5% and 12% - You currently use the Tandem t:slim pump with Control-IQ Technology for at least 2 months - You have internet access and can upload pump data during the study - You are not currently pregnant or breastfeeding (if female) **You may NOT be eligible if...** - You do not use the specific Tandem t:slim Control-IQ pump system - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEControl-IQ insulin pump with Lyumjev insulin

Control-IQ insulin pump with insulin using settings determined by experimental conversion factor

DEVICEControl-IQ insulin pump with Humalog or Novolog

Control-IQ insulin pump with Humalog or Novolog using optimized insulin settings


Locations(1)

University of Virginia Center for Diabetes Technology

Charlottesville, Virginia, United States

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NCT06948760


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