RecruitingNCT06950827

Textbook Outcomes of Right Hemihepatectomy in Patients With Hepatocellular Carcinoma

Textbook Outcomes of Right Hemihepatectomy in Patients With Hepatocellular Carcinoma: a Comparative Study of Laparoscopic and Open Surgery


Sponsor

West China Hospital

Enrollment

400 participants

Start Date

Apr 5, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Although traditional open right hemihepatectomy is a mature technique, the incision is usually very large; Intraoperative bleeding may be excessive, and postoperative liver failure is also prone to occur. In recent years, compared with traditional open surgery, laparoscopic surgery has many advantages, such as smaller surgical incision and faster postoperative recovery. In recent years, more and more centers have gradually transitioned to performing right hemihepatectomy through laparoscopy as much as possible. However, due to the difficulty of the surgery, steep learning curve, and postoperative complications, its adoption is limited to high-capacity surgical centers. Despite significant progress in laparoscopic liver resection technology, its clinical efficacy remains controversial, especially in laparoscopic right hemihepatectomy. More research is needed to confirm the feasibility and safety of this surgery. At present, it is unclear whether there is a difference in textbook outcomes (TO) between HCC patients undergoing open and laparoscopic right hemihepatectomy, and the association between TO and patient survival prognosis.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is reviewing outcomes for patients who undergo a right hemihepatectomy — surgical removal of the right half of the liver — to treat hepatocellular carcinoma (the most common type of primary liver cancer). Researchers are analyzing what factors lead to the best possible outcomes from this major surgery. **You may be eligible if...** - You are 18 years or older - Your liver cancer (hepatocellular carcinoma) is limited to the right side of the liver, confirmed by pathology - You underwent planned (elective) surgical removal of the right liver lobe - Your liver function before surgery was classified as Child-Pugh A or B grade **You may NOT be eligible if...** - Your liver tumor was a different type (such as cholangiocarcinoma, mixed cell cancer, or cancer that spread from elsewhere) - You had prior upper abdominal surgery - Your surgery involved reconstruction of major blood vessels or bile ducts beyond the gallbladder - Your cancer invaded major blood vessels or spread to distant sites Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDURElaparoscopic right hemihepatectomy

Laparoscopic surgery has many advantages, such as small surgical incision and fast postoperative recovery. In recent years, more and more centers have gradually transitioned to performing right hemihepatectomy through laparoscopy as much as possible.


Locations(1)

West China Hospital

Chengdu, Sichuan, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06950827


Related Trials