RecruitingNot ApplicableNCT06951620

Optimizing Aerobic Fitness in Older Adults

Optimizing Aerobic Fitness and Functional Response to Exercise in Older Adults


Sponsor

University of Vermont Medical Center

Enrollment

114 participants

Start Date

Apr 17, 2025

Study Type

INTERVENTIONAL

Summary

Hospitalization and treatment for cardiovascular disease is one of the main contributors to disability in older adults. Moderate intensity continuous aerobic and resistance training have been the cornerstone of cardiac rehabilitation (CR) for decades to remediate hospital-acquired functional deficits, but some groups receive less or minimal functional benefit from this training. The proposed studies seek to optimize recovery of aerobic fitness and physical function among older cardiac patients using a novel high intensity training regimen with the long-term goal of reducing subsequent disability and improving clinical outcomes.


Eligibility

Min Age: 65 Years

Inclusion Criteria3

  • >65 years old
  • ambulatory
  • enrolled in CR at our center following a recent clinical diagnosis of myocardial infarction or percutaneous intervention will be recruited

Exclusion Criteria3

  • have an active malignancy (excluding non-melanoma skin cancer or low grade prostate cancer under surveillance)
  • unwilling to comply with the exercise prescription they may be assigned to
  • have a submaximal performance on entry exercise tolerance test, defined as respiratory exchange ratio <1.0

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Interventions

OTHERHIIT

Patients who recently experienced a myocardial infarction (MI) or percutaneous intervention (PCI; angioplasty, stent placement or valve replacement) and enroll in Phase 2 Cardiac Rehabilitation (CR) may be randomized to High intensity training (HIIT)

OTHERMICT

Patients who recently experienced a myocardial infarction (MI) or percutaneous intervention (PCI; angioplasty, stent placement or valve replacement) and enroll in Phase 2 Cardiac Rehabilitation (CR) may be randomized to Moderate intensity training


Locations(1)

UVMMC Cardiac Rehabilitation

South Burlington, Vermont, United States

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NCT06951620