RecruitingNot ApplicableNCT06951672

AMEND TS Early Feasibility Study

The AMEND TS Early Feasibility Study is a Prospective, Single-arm, Multi-center Study to Evaluate the Safety and Function of the AMEND(TM) Trans-Septal System for MR Reduction; Up to 15 Subjects Will be Enrolled in up to 7 Investigational Centers in the U.S. and Canada With a 30d Safety Endpoint


Sponsor

Valcare Medical Ltd.

Enrollment

15 participants

Start Date

Sep 11, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Valcare Medical AMEND Trans-Septal System is a mitral valve repair annuloplasty ring implanted in a trans-catheter method intended for correction of mitral regurgitation. It is designed to be used as standalone therapy or in combination with other repair treatments.


Eligibility

Min Age: 21 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called This study will evaluate the safety and functionality of the AMEND™ Trans-Septal System for annuloplasty as a therapy for mitral regurgitation. for people with symptomatic functional mr 3 or greater. The study is currently recruiting participants at 11 locations. People eligible for this study include aged 21 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICEThis study will evaluate the safety and functionality of the AMEND™ Trans-Septal System for annuloplasty as a therapy for mitral regurgitation.

The ability to deploy the annuloplasty ring in a percutaneous fashion affords an improved safety profile for surgical candidates, as well as surgical style solution for those patients that are at elevated risk for surgery due to comorbidities and advanced age. This early feasibility study allows treatment of higher risk surgical candidates with a surgical- level annuloplasty repair therapy by the AMEND™ Implant.


Locations(11)

Banner University Medical Center - Phoenix

Phoenix, Arizona, United States

Scripps Health

La Jolla, California, United States

Piedmont Healthcare

Atlanta, Georgia, United States

Ascension St. Vincent

Indianapolis, Indiana, United States

Columbia University Medical Center (CUMC)

New York, New York, United States

Montefiore Medical Center

The Bronx, New York, United States

Oregon Health & Science University (OHSU)

Portland, Oregon, United States

Saint Thomas Research Institute

Nashville, Tennessee, United States

University of Texas Health Science Center (UTH)

Houston, Texas, United States

Methodist Hospital HCA

San Antonio, Texas, United States

Intermountain Health

Murray, Utah, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06951672