RecruitingPhase 4NCT06952556

Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following HTO/DFO/TTO

A Randomized, Single-blind, Single-center Study Measuring the Effects of Adductor Canal Block Combined With IPACK Infiltration Compared to Adductor Canal Block Alone on Post-operative Pain and Opioid Consumption in Patients Undergoing HTO/DFO/TTO


Sponsor

NYU Langone Health

Enrollment

100 participants

Start Date

Apr 28, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

A randomized, single-blind, single-center study measuring the effects of adductor canal block combined with IPACK infiltration compared to adductor canal block alone on post-operative pain and opioid consumption in patients undergoing high tibial osteotomy (HTO)/distal femoral osteotomy (DFO)/tibial tubercle osteotomy (TTO).


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria3

  • Patients between 18 and 75 years of age
  • Patients undergoing HTO/DFO/TTO.
  • American Society of Anesthesiologists (ASA) I or II

Exclusion Criteria14

  • Patients younger than 18 and older than 75.
  • Patients with multi-ligament injury
  • Patients undergoing concomitant cartilage procedure or ACLR.
  • Patients with a history of chronic pain that have used opioids for pain management for 3 months or longer.
  • Patients who are allergic to oxycodone;
  • Patients with diagnosed or self-reported cognitive dysfunction;
  • Patients with a history of neurologic disorder that can interfere with pain sensation;
  • Patients with a history of drug or recorded alcohol abuse;
  • Patients who are unable to understand or follow instructions;
  • Patients with severe liver disease, renal insufficiency, congestive heart failure, and/or significant heart disease;
  • Patients with an allergy or contraindication to any of the medications used in the study, or patients with a contraindication to any study procedures;
  • Patients with a BMI over 45;
  • Any patient that the investigators feel cannot comply with all study related procedures;
  • Any pregnant patient; assessed via urine pregnancy test in the preoperative area as part of standard preoperative surgical protocol;

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Interventions

DRUGACB

15 mL of 0.25% Bupivacaine block of the saphenous nerve injected under ultrasound guidance via adductor canal.

DRUGIPACK block

IPACK block with 20 mL of 0.25% Bupivacaine injected into the Interspace between the Popliteal Artery and Capsule of the Knee


Locations(1)

NYU Langone Health

New York, New York, United States

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NCT06952556


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