RecruitingNCT06955429

Clinical Investigation Measuring the Long Term Clinical Performance and Safety of Biodentine™ XP in Patients Treated for Coronal Restorative or Endodontic Dental Indications.

Observational, Prospective, International and Multicenter Clinical Investigation Measuring the Longterm Clinical Performance and Safety of Biodentine™ XP in Patients Treated for Coronal Restorative or Endodontic Dental Indications.


Sponsor

Septodont

Enrollment

275 participants

Start Date

Oct 23, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this present study is to collect additional data for the post-marketing follow-up of Biodentine™ XP and measure long-term (up to 10 years) performance and safety of the biomaterial in all its indications.


Eligibility

Min Age: 2 Years

Inclusion Criteria3

  • Temporary tooth, from a child ≥ 2 years old, requiring dental restorative treatment with Biodentine™ XP, and/or, Permanent (mature or immature) tooth, from a child or an adult, requiring a dental restorative and/or an endodontic treatment with Biodentine™ XP.
  • Adult patient with a signed informed consent form; For the minor, if in age to understand, an assent is required, and at least one parent or legal representative must consent.
  • Only in France: Subject affiliated or benefiting from a social/health insurance system.

Exclusion Criteria9

  • Patient with one or more documented contraindication to use Biodentine™ XP (Refer to IFU).
  • Inadequate expected tooth lifetime as estimated by the investigator:
  • For a Temporary tooth: high probability of tooth loss within 2 years after treatment with Biodentine™ XP.
  • For a permanent tooth: high probability of tooth loss within 10 years after treatment with Biodentine™ XP.
  • Patient with any systemic disease that may hinder the normal healing process and/or the follow-up.
  • Adult patient under legal protection measures or unable to express his/her consent, and individual deprived of liberty by judicial or administrative decision, as well as individual receiving psychiatric care.
  • Periodontitis (stage 3, 4 or stage 2 grade C).
  • Inability to comply with study procedures.
  • Participation in another interventional clinical investigation that can induce bias in the study results.

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Interventions

DEVICEDental restorative or endodontic treatment requiring Biodentine XP use

In this observational and prospective study, the patients are included since this intervention is schedulded as part of their routine care.


Locations(8)

Queen Astrid Dental Practice

Kraainem, Belgium

UZ Leuven - University hospital

Leuven, Belgium

HCL Lyon

Lyon, France

Cabinet dentaire

Nantes, France

Cabinet dentaire

Paris, France

Hôpital Rotschild

Paris, France

Hôpital Pitié Salpêtrière

Paris, France

CHU Rennes

Rennes, France

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NCT06955429


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