RecruitingNot ApplicableNCT06965673

Assessment of Eye Movements in Stroke Patients and Closed-loop Intervention

Eye-movement Dynamics During Free Viewing as a Biomarker for Assessment of Visuospatial Functions and for Closed-loop Rehabilitation in Stroke


Sponsor

IRCCS San Camillo, Venezia, Italy

Enrollment

30 participants

Start Date

Apr 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The current study evaluates first the assumption that eye-movements during free viewing behavior are potential biomarkers of visuospatial deficits in stroke population. Second, it assesses the feasibility of a novel visual exploration training to ameliorate visuospatial deficits, by exploiting an auditory biofeedback system coupled with online parsed fixations.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Vigilant
  • First unifocal ischemic or hemorragic stroke
  • Presence of maximum two lacunae, clinically silent, smaller than 15 mm. in the structural MRI
  • Evident symptoms in the visual, attentive, memory, motor or language domain supported by the radiological exam

Exclusion Criteria5

  • Previous stroke history, visible at the radiological exam
  • Multifocal deficit
  • Incapacity to remain vigilant during the required assessments
  • Claustrophobia and/or metallic objects which could prevent MRI acquisition
  • Presence of other neurological, psychiatric or medical conditions which may undermine interpretation of behavioral and neuroimaging results

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Interventions

BEHAVIORALVisual exploration training

Visual exploration of natural scenes guided by closed-loop auditory biofeedback through eye-tracking

BEHAVIORALStandard neuropsychological rehabilitation

Standard rehabilitation delivered at the IRCCS San Camillo hospital


Locations(2)

Azienda Ospedaliera di Padova

Padova, PD, Italy

IRCCS San Camillo

Venice-Lido, VE, Italy

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NCT06965673


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