RecruitingNot ApplicableNCT06967545

A One-Arm Open Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior

Sponsor

Massachusetts General Hospital

Enrollment

20 participants

Start Date

Jan 20, 2026

Study Type

INTERVENTIONAL

Conditions

Suicide Attempt Suicide Ideation

Summary

This study aims to evaluate the acceptability, safety, and preliminary efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among adults with recent and frequent suicide ideation.

Eligibility

Min Age: 18 Years

Inclusion Criteria7

Adults ages 18+
Relatively frequent and recent (≥5 days within the past-month) active suicidal thoughts as assessed via SITBI-R.
Willing and able to provide at least one emergency contact (name, phone number, relation).
Owns an Android or iOS smartphone.
Possesses at least occasional access to Wi-Fi-enabled internet for data down/uploads.
Fluent in English and willing to provide informed consent.
Living in the Boston metropolitan area (i.e., ~50 mile radius around Boston, MA)

Exclusion Criteria5

Recent (past 3-month) hypo/manic symptoms or homicidal ideation or lifetime psychosis spectrum diagnosis as assessed via MINI 7.0.2.
Recent acute suicide risk operationalized as affirmative responses to BOTH below items during structured clinical interview AND evaluation by the PI in consultation with Mentors/Advisor Drs. Wilhelm, Kleiman, and/or Bentley:
At any time in past week: ≥ 8/10 current intent to act on suicidal thoughts (0 \["not at all"\] to 10 \["extremely strong"\]); AND
At any time in past week: thought of a specific suicide plan (i.e, known method/means and/or location) with access to lethal means
Impaired vision (e.g., legal blindness), technological illiteracy, or intellectual disability that might impair ability to provide valid data and/or informed consent.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALSmartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S)

Therapeutic Evaluative Conditioning for Suicide (active TEC-S) is a behavioral treatment where participants are given optional access to a computerized task/game where they repeatedly pair suicidal behavior stimuli (pictures, words) with other negative stimuli and self-related stimuli with positive stimuli.