RecruitingPhase 3NCT06968221

Bovine Reinforcement in Stomach, Colorectal and Lung Operation

A Study on the Safety and Efficacy of Using Cingular Bovine Pericardium Anastomosis Reinforcement Membrane for Tissue Reinforcement and Hemostasis at Anastomotic Sites


Sponsor

Shanghai Cingularbio Co. Ltd

Enrollment

172 participants

Start Date

May 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The primary purpose of this prospective, randomized multicenter center study is to evaluate and compare the outcomes of stomach,colorectal and lung anastomoses reinforced with a bioabsorbable staple line reinforcement material compared with standard non-reinforced techniques with respect to the incidence of postoperative hemorrage rate, anastomotic leakage, if applicable.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria2

  • Subjects who will undergo operation with stapled stomach, colorectal anastomosis with or without reinforcement
  • Subjects willing to accept informed consent and willing to attend the follow up

Exclusion Criteria3

  • Subjects who have significant intraoperative hypotension or cardiac events.
  • Subjects with collagen vascular disease, coagulopathy, significant renal or hepatic dysfunction (creatinine \>1.6 or liver enzymes \> 50% upper limit of normal values).
  • Subjects have uncontrolled intra-abdominal infection

Interventions

DEVICEBioabsorbable Staple Line Reinforcemen

cingular Bioabsorbable Staple Line Reinforcement


Locations(1)

Renji hospital affiliated to Shanghai jiaotong Uni school of medicine

Shanghai, China

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NCT06968221


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