RecruitingNCT06971874

The Outcome of Chronic Kidney Disease Patients With Obstructive Sleep Apnea Syndrome

The Epidemiological Patterns of Obstructive Sleep Apnea Syndrome in Patients With Chronic Kidney Disease and Its Impact on Renal Prognosis

Sponsor

Nanfang Hospital, Southern Medical University

Enrollment

356 participants

Start Date

Jul 17, 2025

Study Type

OBSERVATIONAL

Conditions

Chronic Kidney Diseases OSAS (Obstructive Sleep Apneas Syndrome)

Summary

Obstructive sleep apnea (OSA) is highly prevalent in chronic kidney disease (CKD) patients and strongly linked to obesity, metabolic syndrome, and type 2 diabetes. Besides elevating cardiovascular disease risk, OSA may worsen renal function and diminish quality of life, making its understanding critical for CKD patient health. This study will establish a large, long-term cohort of non-dialysis CKD patients to identify OSA risk factors, explore OSA's association with adverse renal outcomes, and determine OSA prevalence and epidemiological characteristics within the CKD population. The findings will provide a scientific foundation for early OSA identification, diagnosis, and intervention in CKD patients.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how obstructive sleep apnea (when breathing repeatedly stops during sleep) affects the health outcomes of people with moderate chronic kidney disease (CKD). **You may be eligible if...** - You are between 18 and 74 years old - You have been diagnosed with stage 3 or 4 chronic kidney disease (reduced kidney function, but not yet on dialysis) **You may NOT be eligible if...** - You already use CPAP (a breathing machine for sleep apnea) or oxygen therapy - You have other sleep disorders like restless leg syndrome - You have severe heart failure, had a heart attack or stroke in the past 3 months, or have serious lung, neurological, liver, or psychiatric conditions - You have had surgery or a serious infection in the past 3 months - You drink heavily (more than 3 drinks/day for women, 4 drinks/day for men) - You take medications that strongly affect sleep (e.g., antipsychotics, antidepressants, opioids) - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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