RecruitingPhase 1NCT06975124

taVNS Effects on Fear Ratings in Naturalistic Context


Sponsor

University of Electronic Science and Technology of China

Enrollment

70 participants

Start Date

Mar 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

During the fear rating task, 70 participants viewed a 600-second horror movie while continuously rating their subjective fear intensity (0-100 scale) every 0.51 seconds (1,170 total ratings). Functional near-infrared spectroscopy (fNIRS) data were simultaneously recorded using the NIRSIT LITE system to monitor cortical hemodynamic responses.


Eligibility

Min Age: 18 YearsMax Age: 30 Years

Inclusion Criteria1

  • Healthy participants without color blindness, current or regular substance or medication use, any current or history of medical or psychiatric disorders and contraindications for MRI.

Exclusion Criteria3

  • Color blindness,
  • Current or regular substance or medication use
  • any current or history of medical or psychiatric disorders and contraindications for MRI

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Interventions

DEVICEtranscutaneous auricular vagus nerve stimulation

Ear clip electrodes attached to the left cymba conchae to target vagus nerve branches.

DEVICESham condition

Electrode placement attached on the left earlobe.


Locations(1)

Nirsit Lite

Chengdu, Sichuan, China

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NCT06975124


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