RecruitingNot ApplicableNCT06975696

Fusion Imaging in Endovascular Thrombectomy for Acute Ischemic Stroke


Sponsor

Region Skane

Enrollment

300 participants

Start Date

Mar 2, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Endovascular thrombectomy (EVT) is the standard of care for acute ischemic stroke (AIS) caused by a large vessel occlusion. Successful recanalization is one of the most important factors for a good patient outcome, especially when obtained within 30 minutes from groin puncture, and the procedural success-rate reaches above 90% at treating centers of excellence. There are however a portion of cases where recanalization is not achieved, which in some cases are attributed to difficult arterial anatomy affecting the ability to catheterize the precerebral target vessel. In the latest angiography platforms, 3D reconstructions of the aortic, cervical and intracranial arteries from the preprocedural CT angiography can be fused with periprocedural 2D digital subtraction angiography and/or fluoroscopy images, so called 2D/3D Fusion imaging. The preparation steps can be done before patient arrival to the angiography suite and the image fusion can be done in less than a minute during patient preparation. Previous observational studies have shown that the use of fusion imaging during EVT procedures may decrease failed target vessel access and increase procedural success rate and first-pass recanalization rate, without prolonging the procedure. The purpose of this study is to assess the use of fusion imaging in EVT procedures and its effect on target vessel access, recanalization success-rate and procedure times.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Age ≥18 years.
  • Eligible for an EVT procedure

Exclusion Criteria2

  • Previous inclusion in this study
  • No access to a preoperative CTA

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Interventions

PROCEDUREStandard endovascular thrombectomy with Fusion

Standard endovacular procedure with the addition of Fusion imaging according to the intended use of the ARTIS Icono Biplane.

PROCEDUREStandard EVT without Fusion

Standard endovacular procedure without the use of Fusion imaging on the ARTIS Icono Biplane.


Locations(4)

Helsinki University Central Hospital

Helsinki, Finland

Turku University Hospital

Turku, Finland

Skane University Hospital Lund

Lund, Sweden

Örebro University Hospital

Örebro, Sweden

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NCT06975696


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