oCular Examination at Cell RESolution With Optical TransmissionTomography
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
300 participants
Nov 12, 2024
INTERVENTIONAL
Conditions
Summary
Understanding the pathogenesis of eye diseases has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems, such as optical coherence tomography (OCT), are limited in terms of resolution, acquisition speed or access to certain eye functions. Our team has participated in the development of a new generation of imaging technology known as optical transmission tomography (OTT), which enables imaging of the anterior parts of the eye with high cellular resolution, a wide field of view and reduced examination delay.
Eligibility
Inclusion Criteria12
- For Patients:
- subjects aged 18 to 80 years;
- Male or female;
- with an ocular disease affecting the cornea, ocular surface, lens (cataract) or glaucoma, or requiring refractive surgery or post-refractive surgery follow-up;
- Are covered by the French Assurance Maladie;
- Have signed an express, free and informed consent form.
- For Healthy volunteers:
- subjects aged 18 to 80 years;
- Male or female;
- Healthy subjects with no known pathology directly or indirectly affecting ocular structures;
- Covered by the French Assurance Maladie.
- Having signed an express, free and informed consent form.
Exclusion Criteria6
- For all participants:
- Inability to hold a still position on a standard ophthalmic chin rest;
- Conjunctivitis or other contagious contact disease in active phase;
- Having an implanted pacemaker or other electronic medical device;
- Having a predisposition to iridocorneal angle closure;
- Vulnerable persons or persons under legal protection (pregnant or breast-feeding women; persons under guardianship,
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Interventions
Multiple imaging sessions added by research using the systems described (OTT) will be carried out by two different operators at different positions during these sessions.
Multiple imaging sessions (OCT) already used in standard of care will be performed by two different operators at different positions during these sessions.
Multiple imaging sessions (SM) already used in standard of care will be performed by two different operators at different positions during these sessions.
Locations(1)
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NCT06976034