Streamlining Radioembolization for Small HCC

This study is testing a simplified approach to a procedure called radioembolization (Y-90) — a type of targeted radiation therapy delivered through the blood vessels — for treating small liver cancers (hepatocellular carcinoma, or HCC 5 cm or smaller). The goal is to make the procedure simpler and more widely accessible. **You may be eligible if...** - You have been diagnosed with HCC (liver cancer) per standard guidelines - Your tumor is 5 cm or smaller - Your liver function is well preserved (Child-Pugh class A) - You are in good performance status (ECOG 0 or 1) - Your blood counts, bilirubin, and kidney function are within acceptable ranges **You may NOT be eligible if...** - Your cancer has invaded the main portal vein or hepatic veins - You have a biliary stent or had bowel surgery involving the bile ducts - You have significant COPD or interstitial lung disease - You have a transjugular intrahepatic portosystemic shunt (TIPS) Talk to your doctor to see if this trial is right for you.