RecruitingNot ApplicableNCT06984952

Effectiveness of ERAS on Postoperative Recovery After Minimally Invasive Gastrectomy

Effectiveness of Enhanced Recovery After Surgery (ERAS) on Postoperative Recovery After Minimally Invasive Gastrectomy: A Multi-center Open-labeled Randomized Controlled Study

Sponsor

Seoul National University Hospital

Enrollment

308 participants

Start Date

Jun 13, 2025

Study Type

INTERVENTIONAL

Conditions

Enhanced Recovery After Surgery Gastrectomy for Gastric Cancer

Summary

This prospective, randomized, open-label, multicenter study is designed to evaluate the impact of an enhanced recovery after surgery (ERAS) protocol on the rate of meeting discharge criteria in patients undergoing minimally-invasive gastrectomy for gastric cancer. We hypothesize that implementation of our ERAS protocol will significantly increase the proportion of patients who meet standardized discharge criteria following minimally-invasive gastrectomy.

Eligibility

Min Age: 19 Years

Inclusion Criteria3

Adults aged ≥19 years scheduled to undergo elective laparoscopic or robotic gastrectomy for gastric cancer
American Society of Anesthesiologists physical status classification I to III
Ability to provide written informed consent, demonstrate understanding of the study protocol, and complete patient-reported outcome measures appropriately

Exclusion Criteria4

Requirement for resection of organs other than the stomach during surgery (except for cholecystectomy)
History of upper abdominal surgery (except for cholecystectomy)
Known hypersensitivity to fentanyl, ropivacaine, acetaminophen, or non-steroidal anti-inflammatory drugs
Determined by the investigator or study personnel to be otherwise unsuitable for participation in the study

Interventions

PROCEDUREERAS protocol

The ERAS protocol includes pre-admission patient education through audiovisual materials; reduction of perioperative fasting duration with preoperative carbohydrate loading and early postoperative oral intake; multimodal prophylaxis for postoperative nausea and vomiting; early removal of surgical drains and intravenous lines; early mobilization; and multimodal analgesia aimed at minimizing postoperative opioid use. The detailed protocol used in this study has been published previously \[https://doi.org/10.5230/jgc.2025.25.e27\].