RecruitingNCT06995833

Durvalumab With or Without Olaparib in Patients With Endometrial Cancers Regulatory Post Marketing Surveillance


Sponsor

AstraZeneca

Enrollment

50 participants

Start Date

Sep 19, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Objectives of this study are to assess the safety and effectiveness of Durvalumab with or without Olaparib (hereinafter "the study drug") in a real world setting in patients who are prescribed with the study drug under the approved indication in Korea. This is a multicenter, prospective, observational, real world treatment study. Patients treated as part of routine practice at Korean healthcare centers by investigators will be identified and considered for inclusion in the study. The period of this study is expected to run for 4 years from the approval date of the indication for this study. Approximately 50 patients are expected to be enrolled during the study. Patient will be followed for approximately 12 months from the first dose or up to 90 days after treatment discontinuation if the study drug is administered for less than 12 months, unless they withdraw consent, are lost to follow-up or death.


Eligibility

Plain Language Summary

Simplified for easier understanding

This is a real-world observational study in South Korea that follows women with endometrial cancer (cancer of the lining of the uterus) who are being treated with durvalumab — an immunotherapy drug — with or without olaparib (a targeted therapy that blocks cancer cell DNA repair). Both drugs are approved for use in Korea. The study monitors how patients do in everyday clinical practice, including any side effects and how well the disease is controlled over time. **You may be eligible if...** - You have endometrial cancer and are receiving durvalumab (with or without olaparib) as prescribed under the approved Korean guidelines - You have provided signed informed consent **You may NOT be eligible if...** - You are participating in another interventional clinical trial at the same time - You are using these medications for a purpose not approved on the Korean drug label Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Research Site

Seoul, South Korea

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NCT06995833


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