Ethnic Specificities of S100B Protein Blood Level in Guadeloupe: Cross-sectional Study in Healthy Subjects
Centre Hospitalier Universitaire de la Guadeloupe
200 participants
Feb 1, 2023
OBSERVATIONAL
Conditions
Summary
Numerous studies have demonstrated the significant contribution of S100B blood level measurement in the management of minor to moderate traumatic brain injuries, notably by reducing the number of cranial computed tomography (CT) scans by at least one-third. However, physiological blood concentrations of the S100B protein may be higher in individuals with a Black phenotype compared to those with Asian or, in particular, Caucasian phenotypes. Assessing S100B protein levels in healthy individuals will help confirm the variability of its physiological concentration according to skin phenotype.
Eligibility
Inclusion Criteria5
- Hospital staff of the University Hospital of Guadeloupe or the Hospital of Basse-Terre
- Age between 18 and 65 years
- Individuals willing to specify their ethnic origin and skin phototype
- Individuals affiliated with or beneficiaries of a social security scheme
- Informed individuals who have given their voluntary, informed, and written consent
Exclusion Criteria5
- Individuals on anticoagulant therapy
- Individuals with a personal history of neurological disease
- Individuals with a personal history of melanoma
- Refusal to participate
- Individuals under guardianship, curatorship, or legal protection
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Locations(2)
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NCT06998381